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An axisymmetric model of ultrasound contrast agent collapse following shell rupture
J. Acoust. Soc. Am. Volume 131, Issue 4, pp. 3385-3385 (2012); (1 page)
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Add to FacebookWidely used spherically symmetric models of ultrasound contrast agents (UCA) are unable to capture complicated collapse behaviors when the UCA shell ruptures. Observations from acoustic passive cavitation detection analysis of collapsing UCAs as well as images from high speed videos of UCA destruction suggest that including spatial asymmetry in the shell interface conditions of models may be useful for studying collapse, onset of fragmentation, and initiation of postexcitation rebound. The concept of lipid shell rupture is incorporated into an axisymmetric boundary element method formulation as a circular hole developing during the growth phase of an initially spherical bubble. The different material interfaces are represented by a spatially varying surface tension due to different pressure discontinuity conditions from the inner gas region to the outer fluid region. Results from the simplified geometrical model simulations demonstrate that shell fragments may influence the evolution of collapsing UCA and indicate the possibility of microbubble jetting following lipid shell rupture. (NIH Grant R37EB002641.)
© 2012 Acoustical Society of America
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